Honorary Professor and Consultant in Anaesthesia and Critical Care, University of Leicester and University Hospitals of Leicester NHS Trust, Leicester UK. I am current editor-in-chief of BJA Education and was previously an editor of the British Journal of Anaesthesia (2008-2017). I am an editorial board member of the British Journal of Anaesthesia and Perioperative Medicine. Other current roles include being co-director of the University of Leicester Diagnostic Development Unit and an expert advisor to the British National Formulary. Previously I have served as a member of the ESA Pharmacology Subcommittee, Chairman of the Vascular Anaesthesia Society of Great Britain & Ireland, and an examiner for the Primary FRCA examiner for the Royal College of Anaesthetists. I have had external examining duties at several universities in the UK as well as for the Post Graduate Institute of Medicine, Colombo, Sri Lanka. In 2011 I was awarded the Macintosh Professorship of the Royal College of Anaesthetists. In addition to many lectures at national meetings in the UK I have given invited talks at several meetings of the European Society of Anaesthesiologists, the World Congress of Anaesthesiologists, the Japanese Society of Intensive Care Medicine, the Irish National Congress of Anaesthesia, the Chinese Society of Anesthesiologists, the European Vascular & Endovascular Society and the International Regulatory Peptide Society. My clinical work is in the general adult ICU at the Leicester Royal Infirmary covering all major acute medical and surgical specialties except cardiac and neurosurgery, with approximately 1500 admissions to ICU per year. Our hospital covers a population of c. 1 million and our Emergency Department has the highest number of attendances per year of any ED in the UK. I have led clinical research in anaesthesia and critical care teams in Leicester and the East Midlands for over 18 years and my current research interests include: novel non-invasive monitoring modalities in acute illness; and the effects of endogenous opioids on vascular function and immune modulation in sepsis. Major collaborators include Professors DG Lambert, T Coats and MR Sims, University of Leicester; Dr Girolamo Calo, University of Ferrara, Italy; and Professor Felipe dal Pizzol, University of Extremo Sul Catarinense, Criciuma, Brazil). I have published over 70 original research articles, 30 book chapters, 30 educational reviews, 10 editorials, 10 review articles and 2 invited journal volumes. I have edited 3 textbooks and most recently was senior editor of the 7th edition of Smith & Aitkenhead’s Textbook of Anaesthesia (published 2019).